KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TXNRD2
All Species:
21.82
Human Site:
S324
Identified Species:
32
UniProt:
Q9NNW7
Number Species:
15
Phosphosite Substitution
Charge Score:
0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9NNW7
NP_006431.2
524
56507
S324
G
R
V
P
D
T
R
S
L
N
L
E
K
A
G
Chimpanzee
Pan troglodytes
XP_001166615
481
51948
T294
P
D
G
Q
L
Q
V
T
W
E
D
C
T
T
G
Rhesus Macaque
Macaca mulatta
NP_001152971
524
56314
S324
G
R
V
P
D
T
R
S
L
N
L
E
K
A
G
Dog
Lupus familis
XP_850181
509
55065
S311
G
R
I
P
E
T
K
S
L
N
L
E
K
A
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9JLT4
524
56434
T324
G
R
V
P
E
T
R
T
L
N
L
E
K
A
G
Rat
Rattus norvegicus
Q9Z0J5
526
56406
N326
G
R
V
P
E
T
R
N
L
N
L
E
K
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
NP_001116163
518
56137
T318
G
R
V
P
D
I
K
T
L
N
L
D
S
V
G
Frog
Xenopus laevis
NP_001080052
504
54666
Y304
G
R
A
A
E
T
Q
Y
L
N
L
E
K
V
G
Zebra Danio
Brachydanio rerio
NP_898895
602
65949
C399
I
A
V
G
R
D
A
C
T
G
K
I
G
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P91938
596
64304
D398
G
R
K
G
L
V
D
D
L
N
L
P
N
A
G
Honey Bee
Apis mellifera
NP_001171496
537
59227
L339
R
K
P
L
T
E
E
L
K
P
E
N
I
G
L
Nematode Worm
Caenorhab. elegans
Q17745
667
74094
A457
E
Y
N
T
I
L
M
A
I
G
R
E
A
V
T
Sea Urchin
Strong. purpuratus
XP_797733
490
53044
L295
R
E
P
E
T
A
Q
L
G
L
D
N
T
G
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P48641
499
53852
T302
A
T
G
R
S
P
N
T
K
R
L
N
L
E
A
Baker's Yeast
Sacchar. cerevisiae
P41921
483
53422
D284
M
N
D
S
K
S
I
D
D
V
D
E
L
I
W
Red Bread Mold
Neurospora crassa
Q873E8
468
50294
G283
G
R
T
P
A
V
E
G
L
G
L
D
K
A
G
Conservation
Percent
Protein Identity:
100
91
98.2
83.2
N.A.
84.5
82.6
N.A.
N.A.
72.9
68.6
47
N.A.
48.9
53
40.7
55.7
Protein Similarity:
100
91.2
99
91.4
N.A.
91.5
90.8
N.A.
N.A.
86
82.2
62.2
N.A.
62.4
68.5
56.2
69.8
P-Site Identity:
100
6.6
100
80
N.A.
86.6
86.6
N.A.
N.A.
60
60
6.6
N.A.
46.6
0
6.6
0
P-Site Similarity:
100
13.3
100
100
N.A.
100
100
N.A.
N.A.
80
73.3
6.6
N.A.
46.6
6.6
20
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
33.7
32.8
34.7
Protein Similarity:
N.A.
N.A.
N.A.
51.7
53
52.4
P-Site Identity:
N.A.
N.A.
N.A.
6.6
6.6
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
13.3
60
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
7
7
7
7
7
7
0
0
0
0
7
44
7
% A
% Cys:
0
0
0
0
0
0
0
7
0
0
0
7
0
0
0
% C
% Asp:
0
7
7
0
19
7
7
13
7
0
19
13
0
0
7
% D
% Glu:
7
7
0
7
25
7
13
0
0
7
7
50
0
7
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
57
0
13
13
0
0
0
7
7
19
0
0
7
13
63
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
7
0
7
0
7
7
7
0
7
0
0
7
7
7
0
% I
% Lys:
0
7
7
0
7
0
13
0
13
0
7
0
44
0
0
% K
% Leu:
0
0
0
7
13
7
0
13
57
7
63
0
13
7
7
% L
% Met:
7
0
0
0
0
0
7
0
0
0
0
0
0
0
0
% M
% Asn:
0
7
7
0
0
0
7
7
0
50
0
19
7
0
0
% N
% Pro:
7
0
13
44
0
7
0
0
0
7
0
7
0
0
0
% P
% Gln:
0
0
0
7
0
7
13
0
0
0
0
0
0
0
0
% Q
% Arg:
13
57
0
7
7
0
25
0
0
7
7
0
0
0
0
% R
% Ser:
0
0
0
7
7
7
0
19
0
0
0
0
7
0
0
% S
% Thr:
0
7
7
7
13
38
0
25
7
0
0
0
13
7
7
% T
% Val:
0
0
38
0
0
13
7
0
0
7
0
0
0
19
7
% V
% Trp:
0
0
0
0
0
0
0
0
7
0
0
0
0
0
7
% W
% Tyr:
0
7
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _